Free Information Kit

Learn more about living with lupus and treatment with BENLYSTA

Already taking BENLYSTA?

Get ongoing support for your treatment journey.

Expand to watch videos from
real lupus patients taking BENLYSTA (belimumab).

Getting Started with BENLYSTA

Ask your doctor if you might be a candidate for treatment with BENLYSTA

  • It is not known if BENLYSTA is safe and effective in people with severe active lupus nephritis or severe active central nervous system lupus. BENLYSTA has not been studied in combination with other biologics or intravenous cyclophosphamide. Use of BENLYSTA is not recommended in these situations.
  • In clinical studies, there have been mixed results regarding how well BENLYSTA works in black/African American patients. Therefore, you should consult with your healthcare provider to determine if BENLYSTA is right for you.

This is not a full list of the things your healthcare professional will need to consider before prescribing BENLYSTA. For more information, refer to the Medication Guide, and talk to your doctor.

Pregnancy and Breastfeeding

Tell your healthcare provider if you are pregnant or plan to become pregnant. It is not known if BENLYSTA will harm your unborn baby. Tell your healthcare provider right away if you become pregnant or you think you may be pregnant while receiving treatment with BENLYSTA.

Tell your healthcare provider if you are breastfeeding or plan to breastfeed. It is not known if BENLYSTA passes into the breast milk. You and your healthcare provider should discuss whether or not you should receive BENLYSTA and breastfeed.

Women of childbearing age should use an effective method of birth control while receiving BENLYSTA and for at least 4 months after the final dose of BENLYSTA.

If you become pregnant while receiving BENLYSTA, talk to your healthcare provider about enrolling in the Pregnancy Registry for BENLYSTA. You can enroll in this registry by calling 1-877-681-6296. The purpose of this registry is to monitor the health of you and your baby.

Before taking BENLYSTA

Your healthcare professional is your partner in treating lupus and managing your symptoms. He or she can help you best if you share information regarding your overall health.

Tell your healthcare professional if:

  • You think you have an infection or have infections that keep coming back. You should not receive BENLYSTA if you have an infection unless your healthcare provider tells you to.
  • You have or have had mental health problems such as depression or thoughts of suicide.
  • You have recently received a vaccination, or think you may need a vaccination. If you are receiving BENLYSTA, you should not receive live vaccines.
  • You are allergic to other medicines.
  • You are receiving other biologic medicines, monoclonal antibodies, or IV infusions of cyclophosphamide (Cytoxan). The use of BENLYSTA with these medications is not recommended.
  • You have or have had any type of cancer.
  • You have any other medical conditions.

Remember to tell your healthcare professional about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

The Infusion Experience

Morgan, Michelle and Susan describe the infusion process and provide helpful tips for passing the time.

Watch Now

Support for BENLYSTA & Advice for Other Lupus Patients

Michelle, Susan and Morgan talk about the help they got from BENLYSTA Gateway, and offer words of advice for other people living with lupus.

Watch Now

GSK sponsors ambassadors, who were on BENLYSTA at the time of filming, and pays them for their time and expense in sharing their experiences. Individual results may vary.

What you may experience with BENLYSTA

Be prepared for your infusion and beyond.

Know the risks

Learn more about the potential risks and side effects of BENLYSTA

What is BENLYSTA?

BENLYSTA is a prescription medication used to treat adults with active systemic lupus erythematosus (SLE or lupus) who are receiving other lupus medicines.

It is not known if BENLYSTA is safe and effective in people with severe active lupus nephritis or severe active central nervous system lupus, and it has not been studied in combination with other biologics or intravenous cyclophosphamide. Use of BENLYSTA is not recommended in these situations.

Do not receive BENLYSTA if you are allergic to belimumab or to any of the ingredients in BENLYSTA.

Important Safety Information

The most important information to know about BENLYSTA

BENLYSTA can cause serious side effects. Some of these side effects may cause death. It is not known if BENLYSTA causes these serious side effects.

Important Safety Information

The most important information to know about BENLYSTA

BENLYSTA can cause serious side effects. Some of these side effects may cause death. It is not known if BENLYSTA causes these serious side effects.

Tell your healthcare provider right away if you have any of the symptoms listed below while receiving BENLYSTA

  • Infections: fever, chills, pain or burning with urination, urinating often, coughing up mucus, shortness of breath, or diarrhea/vomiting.
  • Heart problems: chest discomfort or pain, shortness of breath, cold sweats, nausea, dizziness, or discomfort in other areas of the upper body.
  • Allergic (hypersensitivity) reactions: itching, swelling of the face, lips, mouth, tongue, or throat, trouble breathing, anxiousness, low blood pressure, dizziness or fainting, headache, nausea, or skin rash. Serious allergic reactions can happen on the day of, or in the days after, receiving BENLYSTA and may cause death.
  • Mental health problems and suicide: thoughts of suicide or dying, attempt to commit suicide, trouble sleeping, new or worse anxiety or depression, acting on dangerous impulses, other unusual changes in your behavior or mood, or thoughts of hurting yourself or others.

Before receiving BENLYSTA also discuss with your healthcare provider if you:

  • think you have an infection or have infections that keep coming back. You should not receive BENLYSTA if you have an infection unless your healthcare provider tells you to.
  • have or have had mental health problems such as depression or thoughts of suicide.
  • have recently received a vaccination or if you think you may need a vaccination. If you are receiving BENLYSTA, you should not receive live vaccines.
  • are taking other medicines, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
  • are allergic to other medicines.
  • are receiving other biologic medicines, monoclonal antibodies, or IV infusions of cyclophosphamide (CYTOXAN®).
  • have or have had any type of cancer.
  • have any other medical conditions.
  • are pregnant or plan to become pregnant. It is not known if BENLYSTA will harm your unborn baby. Females who are able to become pregnant should talk to their healthcare provider about whether or not they will use birth control (contraception) and receive BENLYSTA. If BENLYSTA is recommended, you should use an effective method of birth control while receiving BENLYSTA and for at least 4 months after the final dose of BENLYSTA. Tell your healthcare provider right away if you become pregnant during your treatment with BENLYSTA or if you think you may be pregnant. If you become pregnant while receiving BENLYSTA, talk to your healthcare provider about enrolling in the BENLYSTA Pregnancy Registry. You can enroll in this registry by calling 1-877-681-6296. The purpose of this registry is to monitor the health of you and your baby.
  • are breastfeeding or plan to breastfeed. It is not known if BENLYSTA passes into your breast milk. You and your healthcare provider should talk about whether or not you should receive BENLYSTA and breastfeed.

Possible side effects of BENLYSTA

  • Progressive multifocal leukoencephalopathy (PML). PML is a serious and life-threatening brain infection. PML can result in death or severe disability. Tell your healthcare provider right away if you notice any new or worsening medical problems: memory loss, trouble thinking, dizziness or loss of balance, difficulty talking or walking, or loss of vision.
  • Cancer. Medicines that affect the immune system including BENLYSTA, may increase your risk of certain cancers.

The most common side effects of BENLYSTA are nausea, diarrhea, fever, stuffy or runny nose and sore throat, cough, trouble sleeping, leg or arm pain, depression, headache, and pain, redness, itching, or swelling at the site of injection (when given subcutaneously). These are not all the possible side effects of BENLYSTA. Call your doctor for medical advice about side effects.

Other Important Information

In clinical studies, there have been mixed results regarding how well BENLYSTA works in black/African American patients. Therefore, you should consult with your healthcare provider to determine if BENLYSTA is right for you.


Please see Prescribing Information and Medication Guide for BENLYSTA.

For more information, call the BENLYSTA Gateway at 1-877-4-BENLYSTA (1-877-423-6597)
Monday through Friday, 8 AM to 8 PM Eastern Time.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.