Patient Stories

They said, “Sorry lupus, not today.” See how four lupus warriors took the next step and discovered BENLYSTA.

Nicole, real BENLYSTA patient compensated by GSK

Featured patients have been compensated by GSK to share their stories.

Nadine

Enjoys time with her family and dogs
Lupus nephritis
Started BENLYSTA in 2018

Laughter has always been the best medicine for Nadine, but after being diagnosed with lupus nephritis and taking high-dose steroids, she asked her doctor for something different.

Show Transcript

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

Nadine
Real BENLYSTA Patient
Compensated by GSK

NARRATOR:
What is BENLYSTA?
BENLYSTA is a prescription medicine for adults with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis on other lupus medicines. BENLYSTA is not for people with severe active central nervous system lupus.

Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA. Remember to watch the complete video to see additional safety information.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

What is BENLYSTA?
BENLYSTA is a prescription medicine for adults with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis on other lupus medicines. BENLYSTA is not for people with severe active central nervous system lupus.

Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.
Please see complete Prescribing Information, including Medication Guide, at BENLYSTA.com

NADINE:
My name is Nadine. I'm 36 years old, and I live in Florida. Family, fitness, and just being with my dogs is pretty much my life. Fitness has really been my focus though. I live a mile and a half from the beach, so I go every now and then, usually with my fitness family. But my favorite thing to do is laugh. Humor is what has gotten me this far.

ON-SCREEN TEXT:
Real BENLYSTA patient compensated by GSK.

NADINE:
I was first diagnosed with lupus when I was 21. I was at work one day when I started noticing symptoms. My hands were swelling. They were red and hurt a lot. I had never experienced pain like this, so I went directly to the ER for help. Later on, it happened again and I went back to the ER. This time I had the butterfly rash on my face. The ER doctor suggested I see my own doctor and consider getting tested for lupus.

ON-SCREEN TEXT:
Nadine’s diagnosis
Systemic lupus erythematosus (SLE), or lupus, is a chronic autoimmune disease where the immune system mistakenly attacks your own body’s healthy tissues.

ON-SCREEN TEXT:
Symptom
A change a person experiences that may indicate a disease or condition and which may not be visible to themselves or others

ON-SCREEN TEXT:
What Nadine noticed:
Pain in her hands and butterfly rash on her face

NADINE:
I went to a rheumatologist and my test levels clearly pointed to lupus. I asked my doctor to give me medicine for the pain so I could get back to my life. I cried a lot in those days because I had never experienced pain like that. But crying didn't make me feel better; it actually stressed my body more. Getting upset just seemed to make everything worse. I told myself I had to find a different way to handle the pain. I decided I had to laugh through it. Laughing has always been my way of overcoming challenges and tough times. When I was a kid, I was bullied for being overweight but I just laughed through it. I told myself that's how I got through school and that's how I'm going to get through this.

ON-SCREEN TEXT:
Nadine’s Tip
Laugh through the pain.

NADINE:
My primary doctor gave me a steroid for the pain. I didn't know what it was. She told me that it could lead to weight gain. That was frustrating to hear because I had just lost 40 pounds, but I was determined not to let lupus hold me back, so I took the steroid and it helped. I was able to function again and keep moving. But then the water weight came on. I tried to work out more, but I was also having a lot of severe flares that often put me in the hospital. I couldn't work out the way I used to. I started needing to take time away from my job. Still, I was determined to keep going.

ON-SCREEN TEXT:
Lupus began to hold Nadine back

NADINE:
I had lupus for four to five years before I was diagnosed with lupus nephritis. During one of my hospital visits, my 24-hour urine test showed a lot of protein in my urine. My doctor wanted to do a biopsy because she said my lupus might be affecting my kidneys. It occurred to me that I wasn't urinating as frequently and my urine was a lot darker and had a strong smell. I was diagnosed with lupus nephritis. The swelling became more intense over much of my body. What swelled most and hurt the most were my feet. It was excruciating. And this was on top of the joint pain I was already having. To move around I had to use a walker at home. I used a cane, a scooter, and even a wheelchair when I was out and about.

ON-SCREEN TEXT:
Nadine’s diagnosis
Lupus nephritis (lupus-related kidney inflammation) occurs when lupus causes the immune system to attack and inflame the kidneys

ON-SCREEN TEXT:
What Nadine noticed:
Changes in urination and swelling over much of her body

ON-SCREEN TEXT:
Lupus nephritis symptoms include weight gain, swelling, increase in urination (especially at night), blood and foamy appearance in the urine, and high blood pressure

NADINE:
After my lupus nephritis diagnosis, I finally broke down and cried. I have had a lot of medical challenges throughout my life, but never cried. But when I found out I had kidney disease, I felt like this is it, I'm dying now.

NADINE:
I suffered for two to three years with lupus nephritis, and then I just couldn't take it anymore. It seemed like nothing was working so I asked my doctor for something different, something more. Then he told me about BENLYSTA. I had heard about BENLYSTA from my family. My aunt actually sent my mom an article about it. It was from an online journal and talked about BENLYSTA and how it could help people with lupus. I remember that article, so when my doctor mentioned it, I was ready to try it.

ON-SCREEN TEXT:
Nadine’s Tip
If you don’t feel your medicines are working, ask your doctor for something different… something more.
BENLYSTA is an add-on therapy. Results may vary.

ON-SCREEN TEXT:
Nadine’s doctor added BENLYSTA.
BENLYSTA is an add-on therapy. Results may vary.

ON-SCREEN TEXT:
BENLYSTA is not a steroid. When it’s added to your current treatment plan, it can help reduce your symptoms and flares related to lupus.

NARRATOR:
Have you been diagnosed with lupus and or lupus nephritis? Are you currently taking medications to treat your lupus and/or lupus nephritis? Are you still experiencing symptoms and flares? If you answered yes, ask your doctor about adding BENLYSTA.

ON-SCREEN TEXT:
MANAGING YOUR LUPUS STARTS WITH YOU

1. Have you been diagnosed with lupus and/or lupus nephritis?

2. Are you currently taking medications to treat your lupus and/or lupus nephritis?

3. Are you still experiencing symptoms and flares?

If you answered yes, ask your doctor about adding BENLYSTA.

NADINE:
After almost a year of being on BENLYSTA, I started to feel some relief. Tests started showing that I was responding to BENLYSTA and it was helping to reduce my disease activity. The number of severe lupus flares that would have sent me to the hospital started going down.

ON-SCREEN TEXT:
This is Nadine’s experience. Yours may vary.

ON-SCREEN TEXT:
BENLYSTA may also help reduce the number of severe lupus flares you are having.

NARRATOR:
In three clinical studies of adult patients with active lupus, BENLYSTA significantly reduced lupus disease activity, mainly related to improvement in the immune system, muscles, joints, and skin, significantly reduced risk of severe flares in two of the three studies, and reduced steroid dose by 25% or more during Weeks 40 through 52 in patients receiving 7.5 milligrams or higher daily dose of steroid at the start of the studies.

ON-SCREEN TEXT:
LUPUS
In three clinical studies of adult patients with active lupus, BENLYSTA*:

Significantly reduced lupus disease activity mainly related to improvements in the immune system, muscles, joints, and skin.†
Significantly reduced risk of severe flares in two of the three studies.†
Reduced steroid dose by 25% or more (to a daily dose of 7.5 mg or less) during Weeks 40-52, in patients receiving 7.5 mg or higher daily dose of steroid at the start of the studies.†‡

* These studies were used in the FDA approval of BENLYSTA.
† Compared to other lupus medicines alone.
‡ A reduction of steroid dose was seen but was not statistically significant.
Results may vary.

NADINE:
Because BENLYSTA was helping, my doctor said we could reduce my steroid dose. It was hard to believe because I had been on steroids every single day for nearly eight years straight.

ON-SCREEN TEXT:
BENLYSTA may make it possible for your healthcare provider to reduce your steroid dose.
This is Nadine’s experience. Yours may vary.

NARRATOR:
In a two-year clinical study of adult patients with active lupus nephritis, BENLYSTA significantly reduced kidney disease activity with maintained kidney function, reduced protein in the urine, and reduced the need for rescue medicines, and significantly reduced risk of kidney worsening.

ON-SCREEN TEXT:
LUPUS NEPHRITIS
In a 2-year clinical study of adult patients with active lupus nephritis, BENLYSTA:

Significantly reduced kidney disease activity, with maintained kidney function, reduced protein in the urine, and reduced need for rescue medicines.*†
Significantly reduced risk of kidney worsening.*

* Compared to other lupus medicines alone.
† Rescue medicines such as steroids greater than 10 mg/day.
Results may vary.

NADINE:
To stay a step ahead of lupus, you have to stay focused. Go to your doctor's appointments, take your medication. Seriously, take it. It can be hard to remember, but you need to take all of your medications. I never forget to take my BENLYSTA shot. It's too important. I take it on Friday night, right before I go to bed. So it’s the last thing I do for the week. It's also important to move and stay as active as you can and fuel your body with good stuff. Be positive and stay around positive people.

ON-SCREEN TEXT:
Nadine’s Tip
Stay a step ahead of lupus.

NADINE:
If your doctor thinks BENLYSTA could help, I would recommend it. Ultimately you have to make the choice for yourself. And I would say, listen to your intuition and your body. Not every medication is going to work the same for everyone. In my case, BENLYSTA made such a difference for me.

ON-SCREEN TEXT:
Nadine’s Tip
Listen to your body.

NADINE:
If I could say one thing to lupus, I'd say, give me a break and get off my back. I didn't ask for you to come here. Just leave me alone. And that is the nicest way to say it. If I could say one thing to another lupus warrior, find a doctor who listens. You should never feel shy or uncomfortable about talking to your doctor about your treatment.

ON-SCREEN TEXT:
Nadine’s most important advice
Advocate for yourself and your care.

NADINE:
If you have lupus or lupus nephritis, and you're not seeing the results you hope for from your current medications, ask your doctor if BENLYSTA is right for you.

ON-SCREEN TEXT:
Ask your doctor about BENLYSTA.

ON-SCREEN TEXT:
For financial assistance information, visit the Savings & Support tab of BENLYSTA.com.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

Important Safety Information

NARRATOR:
What is BENLYSTA?
BENLYSTA is a prescription medicine for adults with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis on other lupus medicines. BENLYSTA is not for people with severe active central nervous system lupus.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

What is BENLYSTA?
BENLYSTA is a prescription medicine for adults with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis on other lupus medicines. BENLYSTA is not for people with severe active central nervous system lupus.

NARRATOR:
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.

The most important information about BENLYSTA
Immunosuppressive agents, including BENLYSTA, can cause serious side effects. Some of these may cause death.

Infections: fever, chills, pain or burning with urination, urinating often, coughing up mucus, or warm, red, or painful skin or sores on your body. Infections could be serious, leading to hospitalization or death.
Allergic (hypersensitivity) reactions: itching, swelling of the face, lips, mouth, tongue, or throat, trouble breathing, anxiousness, low blood pressure, dizziness or fainting, headache, nausea, or skin rash. Serious allergic reactions can happen the day of, or in days after, receiving BENLYSTA and may cause death.
Mental health problems and suicide: thoughts of suicide or dying, attempt to commit suicide, trouble sleeping (insomnia), new or worse anxiety or depression, acting on dangerous impulses, other unusual changes in your behavior or mood, or thoughts of hurting yourself or others.

Before receiving BENLYSTA, discuss with your healthcare provider if you:

think you have an infection or have infections that keep coming back. Do not use BENLYSTA if you have an infection unless your healthcare provider tells you to.
have or have had mental health problems such as depression or thoughts of suicide.
have recently received or may need a vaccination. If you are receiving BENLYSTA, you should not receive live vaccines.
are taking any medicines, including prescription, over-the-counter, vitamins, and herbal supplements.
are allergic to other medicines
are receiving other biologic medicines.
have or have had any type of cancer.
have any other medical conditions.
are pregnant or plan to become pregnant. It is unknown if BENLYSTA will harm your unborn baby. Talk to your healthcare provider about whether to prevent pregnancy while on BENLYSTA. If you choose to prevent pregnancy, you should use an effective method of birth control for at least 4 months after the final dose of BENLYSTA.
become pregnant while receiving BENLYSTA, talk to your healthcare provider about enrolling in the BENLYSTA Pregnancy Registry. You can enroll in this registry by calling 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/benlysta-belimumab/.
are breastfeeding or plan to breastfeed. It is unknown if BENLYSTA passes into your breast milk.

Possible side effects of BENLYSTA

Progressive multifocal leukoencephalopathy (PML). PML is a serious and life-threatening brain infection. PML can result in death or severe disability. Tell your healthcare provider right away if you notice any new or worsening medical problems: memory loss, trouble thinking, dizziness or loss of balance, difficulty talking or walking, or loss of vision.
Cancer. Medicines that affect the immune system, including BENLYSTA, may increase your risk of certain cancers.

The most common side effects of BENLYSTA are nausea, diarrhea, fever, stuffy or runny nose and sore throat, persistent cough, trouble sleeping, leg or arm pain, depression, headache, and pain, redness, itching, or swelling at the site of injection (when given subcutaneously). These are not all the possible side effects of BENLYSTA. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

ON-SCREEN TEXT:
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.

The most important information about BENLYSTA
IImmunosuppressive agents, including BENLYSTA, can cause serious side effects. Some of these may cause death.

Infections: fever, chills, pain or burning with urination, urinating often, coughing up mucus, or warm, red, or painful skin or sores on your body. Infections could be serious, leading to hospitalization or death.
Allergic (hypersensitivity) reactions: itching, swelling of the face, lips, mouth, tongue, or throat, trouble breathing, anxiousness, low blood pressure, dizziness or fainting, headache, nausea, or skin rash. Serious allergic reactions can happen the day of, or in days after, receiving BENLYSTA and may cause death.
Mental health problems and suicide: thoughts of suicide or dying, attempt to commit suicide, trouble sleeping (insomnia), new or worse anxiety or depression, acting on dangerous impulses, other unusual changes in your behavior or mood, or thoughts of hurting yourself or others.

Before receiving BENLYSTA, discuss with your healthcare provider if you:

think you have an infection or have infections that keep coming back. Do not use BENLYSTA if you have an infection unless your healthcare provider tells you to.
have or have had mental health problems such as depression or thoughts of suicide.
have recently received or may need a vaccination. If you are receiving BENLYSTA, you should not receive live vaccines.
are taking any medicines, including prescription, over-the-counter, vitamins, and herbal supplements.
are allergic to other medicines.
are receiving other biologic medicines.
have or have had any type of cancer.
have any other medical conditions.
are pregnant or plan to become pregnant. It is unknown if BENLYSTA will harm your unborn baby. Talk to your healthcare provider about whether to prevent pregnancy while on BENLYSTA. If you choose to prevent pregnancy, you should use an effective method of birth control for at least 4 months after the final dose of BENLYSTA.
become pregnant while receiving BENLYSTA, talk to your healthcare provider about enrolling in the BENLYSTA Pregnancy Registry. You can enroll in this registry by calling 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/benlysta-belimumab/.
are breastfeeding or plan to breastfeed. It is unknown if BENLYSTA passes into your breast milk.

Possible side effects of BENLYSTA

Progressive multifocal leukoencephalopathy (PML). PML is a serious and life-threatening brain infection. PML can result in death or severe disability. Tell your healthcare provider right away if you notice any new or worsening medical problems: memory loss, trouble thinking, dizziness or loss of balance, difficulty talking or walking, or loss of vision.
Cancer. Medicines that affect the immune system, including BENLYSTA, may increase your risk of certain cancers.

The most common side effects of BENLYSTA are nausea, diarrhea, fever, stuffy or runny nose and sore throat, persistent cough, trouble sleeping, leg or arm pain, depression, headache, and pain, redness, itching, or swelling at the site of injection (when given subcutaneously). These are not all the possible side effects of BENLYSTA. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
For US audiences only.
Trademarks are owned by or licensed to the GSK group of companies.
©2023 GSK or licensor.
BELVID230016 November 2023
Produced in USA.

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If your doctor thinks BENLYSTA could help, I would recommend it."

Stephanie

Enjoys being an active mom
Lupus
Started BENLYSTA in 2017

Stephanie lives a busy life, so she needed a treatment she could take at a time that worked better for her. When her doctor told her about at-home administration, she was ready to try it.

Managing Lupus
Starting BENLYSTA

Show Transcript

NARRATOR:
What is BENLYSTA?
BENLYSTA is a prescription medicine used to treat people with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis (lupus-related kidney inflammation) who are receiving other lupus medicines. It’s unknown if BENLYSTA is safe/effective in children under 5 years when given in a vein or under 18 years when given under the skin. BENLYSTA is not for people with severe active central nervous system lupus.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

What is BENLYSTA?
BENLYSTA is a prescription medicine used to treat people with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis (lupus-related kidney inflammation) who are receiving other lupus medicines. It’s unknown if BENLYSTA is safe/effective in children under 5 years when given in a vein or under 18 years when given under the skin. BENLYSTA is not for people with severe active central nervous system lupus.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA. Please see complete Prescribing Information, including Medication Guide, at BENLYSTA.com.

NARRATOR:
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.
Remember to watch the complete video to see additional safety information.

STEPHANIE:
Hi, I'm Stephanie. I'm 32 and I live in Texas. This is my experience.

ON-SCREEN TEXT:
Real patient compensated by GSK.

STEPHANIE:
I grew up dancing with my sister and I just love to move around and be active. When I was in college, I could tell something was wrong. My joints were hurting and I wasn't able to move the way I used to move.

STEPHANIE:
I was diagnosed in 2011 when I was 23 with systemic lupus. It was a stressful time because I was in my last year of grad school. I was just about to graduate. Infections all the time. It was one thing after another.

STEPHANIE:
My mom told me to go see a rheumatologist because my primary doctor wasn't able to diagnose the problem. The rheumatologist did a series of tests and abruptly one day told me just matter of fact, "You have lupus."

STEPHANIE:
I knew what lupus was before the diagnosis, but I am the first person in my family to have it. I was terrified and just confused. I felt really alone.

STEPHANIE:
I was diagnosed on a Friday and I remember my mom dropped everything she was doing and drove four hours to me at grad school. I'll never forget it.

STEPHANIE:
So I have a positive outlook on life. Often when people meet me, they have no idea I have lupus.

STEPHANIE:
So I'm a busy mom. I'm active, I'm always doing something, and I don't want to be reminded that I have lupus all the time.

STEPHANIE:
I have three tips that help me maintain my lupus. I maintain my stress, delegate tasks, and definitely stay organized.

ON-SCREEN TEXT:
HOW STEPHANIE DOES IT
1. Maintain my stress
2. Delegate tasks
3. Stay organized

STEPHANIE:
My life is super busy. I’m a wife and a mom, and I work full time with a lot of other activities.

STEPHANIE:
I have an amazing support system. My husband, my mom and dad and my sister are always there to support me.

STEPHANIE:
I try to get ahead of it and ask for help rather than try to do it all on my own because the moment I get stressed, that's when it pushes me over the edge.

STEPHANIE:
BENLYSTA helps, too. My doctor brought up BENLYSTA a few times, but I wasn't interested because I thought it was only available in an infusion. Scheduling monthly appointments wasn't for me. So I kept saying no. My doctor told me about the subcutaneous injection, and at that point, I was interested in learning more.

ON-SCREEN TEXT:
This is Stephanie’s experience. Yours may vary

ON-SCREEN TEXT:
BENLYSTA is an add-on therapy. Results may vary.

STEPHANIE:
What I love about it is being able to use it whenever I need to and how easy it is to access it at home. I do my injection every Friday because that's the day that works best for me. What I love about it is just the versatility of it, being able to grab it and keep going on with my day.

STEPHANIE:
I always have my phone in my hand, so I set two reminders, one weekly reminder to take it out of the refrigerator 30 minutes before my injection, and another reminder to actually take the injection. I do the reminders because I'm so busy and I love that BENLYSTA allows me to live my life and just schedule a quick reminder in my day. It doesn't slow me down.

ON-SCREEN TEXT:
STEPHANIE’S TIPS
1 Weekly Reminder 1: Take your dose out of the fridge
2 Weekly Reminder 2: Take your dose

STEPHANIE:
I think of lupus as a speed bump and not a stop sign. That's the best way for me to describe it because it didn't stop my life. It has taught me how to maneuver and manage my stress levels so that I can still live my life.

STEPHANIE:
If I could tell lupus one thing, I would say thank you because, you thought you would stop me, but really you were just a speed bump to slow me down. You taught me how to manage my time, you taught me how to prioritize myself, and you taught me to remember that I'm the most important thing. So instead of being mad at lupus, I'm like, thanks for coming. You've taught me a lesson and you can stay, but now you’re along for my ride. “Sorry, Lupus. You don't get to run this show.”

NARRATOR:
Ready to say, "Sorry, Lupus”? Whether you have lupus or lupus nephritis, adding BENLYSTA may help. Financial assistance is available. Ask your doctor about BENLYSTA.

ON-SCREEN TEXT:
ASK YOUR DOCTOR ABOUT BENLYSTA

ON-SCREEN TEXT:
For financial assistance information, visit the Savings & Support tab of BENLYSTA.com.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
Important Safety Information

NARRATOR:
What is BENLYSTA?
BENLYSTA is a prescription medicine used to treat people with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis (lupus-related kidney inflammation) who are receiving other lupus medicines. It’s unknown if BENLYSTA is safe/effective in children under 5 years when given in a vein or under 18 years when given under the skin. BENLYSTA is not for people with severe active central nervous system lupus.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

What is BENLYSTA?
BENLYSTA is a prescription medicine used to treat people with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis (lupus-related kidney inflammation) who are receiving other lupus medicines. It’s unknown if BENLYSTA is safe/effective in children under 5 years when given in a vein or under 18 years when given under the skin. BENLYSTA is not for people with severe active central nervous system lupus.

NARRATOR:
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.
The most important information about BENLYSTA
Immunosuppressive agents, including BENLYSTA, can cause serious side effects. Some of these may cause death.
Infections: fever, chills, pain or burning with urination, urinating often, coughing up mucus, or warm, red, or painful skin or sores on your body. Infections could be serious, leading to hospitalization or death.
Allergic (hypersensitivity) reactions: itching, swelling of the face, lips, mouth, tongue, or throat, trouble breathing, anxiousness, low blood pressure, dizziness or fainting, headache, nausea, or skin rash. Serious allergic reactions can happen the day of, or in days after, receiving BENLYSTA and may cause death.
Mental health problems and suicide: thoughts of suicide or dying, attempt to commit suicide, trouble sleeping (insomnia), new or worse anxiety or depression, acting on dangerous impulses, other unusual changes in your behavior or mood, or thoughts of hurting yourself or others.
Before receiving BENLYSTA , discuss with your healthcare provider if you:

think you have an infection or have infections that keep coming back. Do not use BENLYSTA if you have an infection unless your healthcare provider tells you to.
have or have had mental health problems such as depression or thoughts of suicide.
have recently received or may need a vaccination. If you are receiving BENLYSTA, you should not receive live vaccines.
are taking any medicines, including prescription, over-the-counter, vitamins, and herbal supplements.
are allergic to other medicines.
are receiving other biologic medicines.
have or have had any type of cancer.
have any other medical conditions.
are pregnant or plan to become pregnant. It is unknown if BENLYSTA will harm your unborn baby. Talk to your healthcare provider about whether to prevent pregnancy while on BENLYSTA. If you choose to prevent pregnancy, you should use an effective method of birth control for at least 4 months after the final dose of BENLYSTA.
become pregnant while receiving BENLYSTA, talk to your healthcare provider about enrolling in the BENLYSTA Pregnancy Registry. You can enroll in this registry by calling 1-877-311-8972 or go to mothertobaby.org/ongoing-study/benlysta-belimumab/.
are breastfeeding or plan to breastfeed. It is unknown if BENLYSTA passes into your breast milk.

Possible side effects of BENLYSTA

Progressive multifocal leukoencephalopathy (PML). PML is a serious and life-threatening brain infection. PML can result in death or severe disability. Tell your healthcare provider right away if you notice any new or worsening medical problems: memory loss, trouble thinking, dizziness or loss of balance, difficulty talking or walking, or loss of vision.
Cancer. Medicines that affect the immune system, including BENLYSTA, may increase your risk of certain cancers.

The most common side effects of BENLYSTA are nausea, diarrhea, fever, stuffy or runny nose and sore throat, persistent cough, trouble sleeping, leg or arm pain, depression, headache, and pain, redness, itching, or swelling at the site of injection (when given subcutaneously). These are not all the possible side effects of BENLYSTA. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

ON-SCREEN TEXT:
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.
The most important information about BENLYSTA
Immunosuppressive agents, including BENLYSTA, can cause serious side effects. Some of these may cause death.

Infections: fever, chills, pain or burning with urination, urinating often, coughing up mucus, or warm, red, or painful skin or sores on your body. Infections could be serious, leading to hospitalization or death.
Allergic (hypersensitivity) reactions: itching, swelling of the face, lips, mouth, tongue, or throat, trouble breathing, anxiousness, low blood pressure, dizziness or fainting, headache, nausea, or skin rash. Serious allergic reactions can happen the day of, or in days after, receiving BENLYSTA and may cause death.
Mental health problems and suicide: thoughts of suicide or dying, attempt to commit suicide, trouble sleeping (insomnia), new or worse anxiety or depression, acting on dangerous impulses, other unusual changes in your behavior or mood, or thoughts of hurting yourself or others.

Before receiving BENLYSTA, discuss with your healthcare provider if you:

think you have an infection or have infections that keep coming back. Do not use BENLYSTA if you have an infection unless your healthcare provider tells you to.
have or have had mental health problems such as depression or thoughts of suicide.
have recently received or may need a vaccination. If you are receiving BENLYSTA, you should not receive live vaccines.
are taking any medicines, including prescription, over-the-counter, vitamins, and herbal supplements.
are allergic to other medicines.
are receiving other biologic medicines.
have or have had any type of cancer.
have any other medical conditions.
are pregnant or plan to become pregnant. It is unknown if BENLYSTA will harm your unborn baby. Talk to your healthcare provider about whether to prevent pregnancy while on BENLYSTA. If you choose to prevent pregnancy, you should use an effective method of birth control for at least 4 months after the final dose of BENLYSTA.
become pregnant while receiving BENLYSTA, talk to your healthcare provider about enrolling in the BENLYSTA Pregnancy Registry. You can enroll in this registry by calling 1-877-311-8972 or go to mothertobaby.org/ongoing-study/benlysta-belimumab/.
are breastfeeding or plan to breastfeed. It is unknown if BENLYSTA passes into your breast milk.

Possible side effects of BENLYSTA

Progressive multifocal leukoencephalopathy (PML). PML is a serious and life-threatening brain infection. PML can result in death or severe disability. Tell your healthcare provider right away if you notice any new or worsening medical problems: memory loss, trouble thinking, dizziness or loss of balance, difficulty talking or walking, or loss of vision.
Cancer. Medicines that affect the immune system, including BENLYSTA, may increase your risk of certain cancers.

The most common side effects of BENLYSTA are nausea, diarrhea, fever, stuffy or runny nose and sore throat, persistent cough, trouble sleeping, leg or arm pain, depression, headache, and pain, redness, itching, or swelling at the site of injection (when given subcutaneously). These are not all the possible side effects of BENLYSTA. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
For US audiences only.
Trademarks are owned by or licensed to the GSK group of companies.
©2023 GSK or licensor.
BELVID230018 November 2023
Produced in USA.

close

Sorry, lupus. You don't get to run this show today.”

Show Transcript

NARRATOR:
What is BENLYSTA?
BENLYSTA is a prescription medicine used to treat people with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis (lupus-related kidney inflammation) who are receiving other lupus medicines. It’s unknown if BENLYSTA is safe and effective in children under 5 years when given in a vein or under 18 years when given under the skin. BENLYSTA is not for people with severe active central nervous system lupus.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

What is BENLYSTA?
BENLYSTA is a prescription medicine used to treat people with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis (lupus-related kidney inflammation) who are receiving other lupus medicines. It’s unknown if BENLYSTA is safe/effective in children under 5 years when given in a vein or under 18 years when given under the skin. BENLYSTA is not for people with severe active central nervous system lupus.

NARRATOR:
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.

Please click the Important Safety Information tab to the left to watch or hear the Important Safety Information about BENLYSTA.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.
Please see complete Prescribing Information, including Medication Guide, at BENLYSTA.com

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
What I like about BENLYSTA SC

STEPHANIE:
Hi, I'm Stephanie, I'm 32 and I live in Texas. I started BENLYSTA in 2017. This is my experience. My doctor brought up BENLYSTA a few times, but I wasn't interested because I thought it was only available via infusion. Knowing that I had to do a monthly infusion appointment, I knew it would slow me down. Finally, my doctor said that there was a subcutaneous injection that I could use at home, and that's why I finally agreed. My doctor showed me how to do the injection and what works for me is I can schedule it on my life, on my terms. Being able to grab it and keep going with my day works for me. I also liked that it comes directly to my house because it comes from the specialty pharmacy.

ON-SCREEN TEXT:
Real patient compensated by GSK.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
Getting started with a Specialty Pharmacy

STEPHANIE:
Getting BENLYSTA from a specialty pharmacy is different than going to a neighborhood pharmacy to pick your medication up. First, my doctor's office works with my insurance company to get approval.

ON-SCREEN TEXT:
SPECIALTY PHARMACY
Pharmacies that dispense particular medications for certain conditions.
Real patient compensated by GSK.

STEPHANIE:
Then once it was approved, the specialty pharmacy called me. They needed to speak with me so they could ship my BENLYSTA. They collected my co-pay and confirmed my shipment.

STEPHANIE:
I didn't recognize the number the first time so I had to call them back. After that I put the number in my phone so that I would answer when they called. I don't like to answer calls from numbers that I don't know.

ON-SCREEN TEXT:
STEPHANIE’S TIPS
1. Answer your phone when the specialty pharmacy calls.
2. Be sure to return their calls.
3. Add them as a contact in your phone.

STEPHANIE:
I had a lot of questions, things like, what do I need to do to get future refills? When should I expect to get my BENLYSTA? I also asked if there was additional support to help me pay for BENLYSTA, and that's how I learned about the BENLYSTA Copay Program. You can sign up online or BENLYSTA Cares can help.

NARRATOR:
To participate in the BENLYSTA Copay Program, work with your doctor to enroll in BENLYSTA Gateway or go to www.GSKCopayPrograms.com to register and see if you're eligible. Renewal is once a year.

ON-SCREEN TEXT:
The BENLYSTA Copay Program may help eligible commercially insured patients with their out-of-pocket costs for BENLYSTA.

Eligibility restrictions and program maximums apply. Visit www.GSKCopayPrograms.com for complete Program Terms and Conditions.

STEPHANIE:
If you need help, you can always call BENLYSTA Cares. They can help you figure out all kinds of things and put you in touch with BENLYSTA Gateway for copay assistance and help with understanding your insurance.

ON-SCREEN TEXT:
BENLYSTA Cares is here to support you with:

navigating insurance coverage
copay assistance
access to nurse/telehealth resources
on-demand self-injection support
answers, information, tips, and tools

Nurses from BENLYSTA Cares do not give medical advice, and will direct you to your healthcare provider for any disease-, treatment-, or referral-related questions.

STEPHANIE:
To get my BENLYSTA I have two options. One, they can ship it to my local drug store; two, they can send it where it's convenient for me. I have it sent directly to my house. You can have it sent to your office as another option. They make it convenient for me and everything is packed with ice packs.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
Stephanie’s tips for working with your Specialty Pharmacy

STEPHANIE:
Here are my tips to work with your specialty pharmacy. Most pharmacies offer programs to help you remember to fill your prescription. They may even call you and text you to remind you, “Hey, it's time to refill your prescription." I called the specialty pharmacy to see if they had autofill option. I also put a reminder in my phone, a monthly reminder to say, "Hey, it's time to order it.” I left a note with the specialty pharmacy and the shipping company to let them know to leave the medication at the door. One time the shipping company took it with them because I wasn't there to sign for it. It works because I have a porch for them to leave it. The specialty pharmacy I use is very proactive. If I call them and tell them when I need my dose, they make sure that it's there. When I was behind on ordering it, they overnighted it. They do a really great job of understanding the importance of these type of medications.

ON-SCREEN TEXT:
SPECIALTY PHARMACY TIPS
1. Use autofill
2. Let them help you
BENLYSTA may be stored outside of the refrigerator up to 86°F for up to 12 hours if protected from sunlight.

STEPHANIE:
When I'm ready to do my injection, my autoinjector is here at the house, so I'm ready to pull it out of the fridge. I like that it's easy to deal with. I schedule my injections. I do them every Friday because that's the day that works for me.

STEPHANIE:
I live with the phone in my hand, so I might as well put it to work. This is what I do to remember when I'm running on all cylinders and I'm super busy. Maybe this would work for you too. I put two weekly reminders in my phone. One to take the dose out of the fridge, 30 minutes before, and another reminder to take the dose.

ON-SCREEN TEXT:
STEPHANIE’S TIPS
1 Weekly Reminder 1: Take your dose out of the fridge.
2 Weekly Reminder 2. Take your dose.

STEPHANIE:
I'm definitely glad there's a specialty pharmacy handling getting the BENLYSTA to me. It's different than picking up a prescription at a pharmacy, but I like that it’s at my door when I need it.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
Important Safety Information

NARRATOR:
What is BENLYSTA?
BENLYSTA is a prescription medicine used to treat people with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis (lupus-related kidney inflammation) who are receiving other lupus medicines. It’s unknown if BENLYSTA is safe and effective in children under 5 years when given in a vein or under 18 years when given under the skin. BENLYSTA is not for people with severe active central nervous system lupus.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

What is BENLYSTA?
BENLYSTA is a prescription medicine used to treat people with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis (lupus-related kidney inflammation) who are receiving other lupus medicines. It’s unknown if BENLYSTA is safe/effective in children under 5 years when given in a vein or under 18 years when given under the skin. BENLYSTA is not for people with severe active central nervous system lupus.

NARRATOR:
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.
The most important information about BENLYSTA
Immunosuppressive agents, including BENLYSTA, can cause serious side effects. Some of these may cause death.
Infections: fever, chills, pain or burning with urination, urinating often, coughing up mucus, or warm, red, or painful skin or sores on your body. Infections could be serious, leading to hospitalization or death.
Allergic (hypersensitivity) reactions: itching, swelling of the face, lips, mouth, tongue, or throat, trouble breathing, anxiousness, low blood pressure, dizziness or fainting, headache, nausea, or skin rash. Serious allergic reactions can happen the day of, or in days after, receiving BENLYSTA and may cause death.
Mental health problems and suicide: thoughts of suicide or dying, attempt to commit suicide, trouble sleeping (insomnia), new or worse anxiety or depression, acting on dangerous impulses, other unusual changes in your behavior or mood, or thoughts of hurting yourself or others.
Before receiving BENLYSTA, discuss with your healthcare provider if you:

think you have an infection or have infections that keep coming back. Do not use BENLYSTA if you have an infection unless your healthcare provider tells you to.
have or have had mental health problems such as depression or thoughts of suicide.
have recently received or may need a vaccination. If you are receiving BENLYSTA, you should not receive live vaccines.
are taking any medicines, including prescription, over-the-counter, vitamins, and herbal supplements.
are allergic to other medicines.
are receiving other biologic medicines.
have or have had any type of cancer.
have any other medical conditions.
are pregnant or plan to become pregnant. It is unknown if BENLYSTA will harm your unborn baby. Talk to your healthcare provider about whether to prevent pregnancy while on BENLYSTA. If you choose to prevent pregnancy, you should use an effective method of birth control for at least 4 months after the final dose of BENLYSTA.
become pregnant while receiving BENLYSTA, talk to your healthcare provider about enrolling in the BENLYSTA Pregnancy Registry. You can enroll in this registry by calling 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/benlysta-belimumab/.
are breastfeeding or plan to breastfeed. It is unknown if BENLYSTA passes into your breast milk.

Possible side effects of BENLYSTA

Progressive multifocal leukoencephalopathy (PML). PML is a serious and life-threatening brain infection. PML can result in death or severe disability. Tell your healthcare provider right away if you notice any new or worsening medical problems: memory loss, trouble thinking, dizziness or loss of balance, difficulty talking or walking, or loss of vision.
Cancer. Medicines that affect the immune system, including BENLYSTA, may increase your risk of certain cancers.

The most common side effects of BENLYSTA are nausea, diarrhea, fever, stuffy or runny nose and sore throat, persistent cough, trouble sleeping, leg or arm pain, depression, headache, and pain, redness, itching, or swelling at the site of injection (when given subcutaneously). These are not all the possible side effects of BENLYSTA. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

ON-SCREEN TEXT:
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.
The most important information about BENLYSTA
Immunosuppressive agents, including BENLYSTA, can cause serious side effects. Some of these may cause death.

Infections: fever, chills, pain or burning with urination, urinating often, coughing up mucus, or warm, red, or painful skin or sores on your body. Infections could be serious, leading to hospitalization or death.
Allergic (hypersensitivity) reactions: itching, swelling of the face, lips, mouth, tongue, or throat, trouble breathing, anxiousness, low blood pressure, dizziness or fainting, headache, nausea, or skin rash. Serious allergic reactions can happen the day of, or in days after, receiving BENLYSTA and may cause death.
Mental health problems and suicide: thoughts of suicide or dying, attempt to commit suicide, trouble sleeping (insomnia), new or worse anxiety or depression, acting on dangerous impulses, other unusual changes in your behavior or mood, or thoughts of hurting yourself or others.

Before receiving BENLYSTA, discuss with your healthcare provider if you:

think you have an infection or have infections that keep coming back. Do not use BENLYSTA if you have an infection unless your healthcare provider tells you to.
have or have had mental health problems such as depression or thoughts of suicide.
have recently received or may need a vaccination. If you are receiving BENLYSTA, you should not receive live vaccines.
are taking any medicines, including prescription, over-the-counter, vitamins, and herbal supplements.
are allergic to other medicines.
are receiving other biologic medicines.
have or have had any type of cancer.
have any other medical conditions.
are pregnant or plan to become pregnant. It is unknown if BENLYSTA will harm your unborn baby. Talk to your healthcare provider about whether to prevent pregnancy while on BENLYSTA. If you choose to prevent pregnancy, you should use an effective method of birth control for at least 4 months after the final dose of BENLYSTA.
become pregnant while receiving BENLYSTA, talk to your healthcare provider about enrolling in the BENLYSTA Pregnancy Registry. You can enroll in this registry by calling 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/benlysta-belimumab/.
are breastfeeding or plan to breastfeed. It is unknown if BENLYSTA passes into your breast milk.

Possible side effects of BENLYSTA

Progressive multifocal leukoencephalopathy (PML). PML is a serious and life-threatening brain infection. PML can result in death or severe disability. Tell your healthcare provider right away if you notice any new or worsening medical problems: memory loss, trouble thinking, dizziness or loss of balance, difficulty talking or walking, or loss of vision.
Cancer. Medicines that affect the immune system, including BENLYSTA, may increase your risk of certain cancers.

The most common side effects of BENLYSTA are nausea, diarrhea, fever, stuffy or runny nose and sore throat, persistent cough, trouble sleeping, leg or arm pain, depression, headache, and pain, redness, itching, or swelling at the site of injection (when given subcutaneously). These are not all the possible side effects of BENLYSTA. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
For US audiences only.
Trademarks are owned by or licensed to the GSK group of companies.
©2023 GSK or licensor.
BELVID230029 October 2023
Produced in USA.

close

Elijah

Enjoys photography and his motorcycle
Lupus nephritis
BENLYSTA clinical trial participant

Elijah is a free spirit with a big heart who lost his mom to lupus-related complications. After receiving his own diagnosis of lupus nephritis, he wanted to take action to better manage his lupus nephritis with a different kind of treatment.

Show Transcript

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

Elijah
Real BENLYSTA Patient
Compensated by GSK

NARRATOR:
What is BENLYSTA?
BENLYSTA is a prescription medicine for adults with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis on other lupus medicines. BENLYSTA is not for people with severe active central nervous system lupus.

Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.

Remember to watch the complete video to see additional safety information.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.
Please see complete Prescribing Information, including Medication Guide, at BENLYSTA.com

ELIJAH:
Hi, my name is Elijah, but people call me “Tiger.” I'm 30 years old and I live in New York. I live with my three cats and my dog, and I'm a big family person. I think of myself as a free spirit. I like to try new things. I get bored pretty quick. I love riding motorcycles so you may see me out for a ride.

ON-SCREEN TEXT:
Real BENLYSTA patient compensated by GSK.

ELIJAH:
I was diagnosed with lupus when I was in high school. By then, I had already lost my mom who passed away from complications of lupus. So I knew what this disease could do to you physically and emotionally. And what a diagnosis could ultimately mean for me, my family, and my future.

ON-SCREEN TEXT:
Elijah’s diagnosis
Systemic lupus erythematosus (SLE), or lupus, is a chronic autoimmune disease where the immune system mistakenly attacks your own body’s healthy tissues.

ELIJAH:
It took me a while to get diagnosed. At first, I didn't have the typical symptoms. I was having heart problems and went to the hospital. That led to more testing. I went to several doctors. After a few months, I began having more common lupus symptoms like a red rash, the butterfly rash, and hair loss. When I told my doctors that I had lost my mom to lupus, they started to run tests and that's how I was diagnosed with lupus. I was petrified and my family was crushed and scared. Everyone wanted to take care of me. I think they thought I was going to die. My dad was especially overprotective because of what happened of my mom.

ON-SCREEN TEXT:
Symptom
A change a person experiences that may indicate a disease or condition and which may not be visible to themselves or others

ON-SCREEN TEXT:
What Elijah noticed:
Butterfly rash on his face

ELIJAH:
My doctor prescribed steroids and I had a heart monitor. I had doctor's appointments maybe twice a week for at least a couple of years. I was seeing a cardiologist and a rheumatologist. The steroids caused a lot of swelling and water weight gain. I got noticeable stress marks on much of my body that looked like tiger stripes. That's how I got the nickname “Tiger.”

ON-SCREEN TEXT:
For many people with lupus, one of the first treatment options is corticosteroids, such as prednisone, to suppress the immune system and decrease inflammation.

ON-SCREEN TEXT:
Lupus caused Elijah to slow down

ELIJAH:
I started to slow down. I was in a serious relationship that got complicated. I had a new job, but then I really couldn't work much. Everything was really good. But after I got diagnosed, things really changed.

ELIJAH:
Then, one day I started having pain in my lower back. I went to the bathroom and there was blood in my urine. It wasn't completely red, but it was pinkish. I went to the doctor for blood work and he found creatinine and protein in my urine. I had a kidney biopsy and it showed scar tissue on my kidneys. I knew there was a kidney disease associated with lupus, but I didn't know anything about it until I was diagnosed with lupus nephritis. At this time, I felt like my doctors weren't even listening to me. They weren't taking into account my symptoms, my blood work, and how I was feeling all together.

ON-SCREEN TEXT:
Elijah’s lupus changed
What Elijah noticed:
Lower back pain and blood in urine

ON-SCREEN TEXT:
Elijah’s diagnosis
Lupus nephritis (lupus-related kidney inflammation) occurs when lupus causes the immune system to attack and inflame the kidneys

ELIJAH:
Then, I found a doctor who changed my life. He wanted to reduce the steroids and try something different.

ON-SCREEN TEXT:
Elijah’s Tip
Don’t settle—find the doctor who listens and considers your symptoms and test results together.

NARRATOR:
Have you been diagnosed with lupus and or lupus nephritis? Are you currently taking medications to treat your lupus and or lupus nephritis? Are you still experiencing symptoms and flares? If you answered yes, ask your doctor about adding BENLYSTA.

ON-SCREEN TEXT:
MANAGING YOUR LUPUS STARTS WITH YOU
1. Have you been diagnosed with lupus and/or lupus nephritis?
2. Are you currently taking medications to treat your lupus and/or lupus nephritis?
3. Are you still experiencing symptoms and flares?

If you answered yes, ask your doctor about adding BENLYSTA.

ELIJAH:
My new doctor told me about BENLYSTA and a new clinical trial for people with lupus nephritis. The doctor was hopeful that BENLYSTA would help get my lupus nephritis under control, help manage other lupus symptoms and help me to reduce the amount of steroids I needed over time. I saw being a part of the trial as a chance to help myself and other people. Because if I can help someone, I will, especially when it comes to fighting for other patients with lupus nephritis.

ON-SCREEN TEXT:
Elijah took action. His doctor added BENLYSTA.
BENLYSTA is an add-on therapy. Results may vary.

ON-SCREEN TEXT:
BENLYSTA is not a steroid. When it’s added to your current treatment plan, it can help reduce your symptoms and flares related to lupus.

ELIJAH:
We need all the people who can fight. I thought about my mom too. I wonder if a clinical trial like this might have helped her. I've always strived to do what I felt would make my mom proud, because that was the way she raised me. Even the short amount of time I had with her shaped me into the person I am today. So I decided to be part of the trial. BENLYSTA has been helping and unless the doctor says there's no other reason for me to be on it, I have no reason to stop taking it. I'm fighting lupus for the long term, and I can take BENLYSTA to help me keep up the fight.

ON-SCREEN TEXT:
This is Elijah’s experience. Yours may vary.

NARRATOR:
In three clinical studies of adult patients with active lupus, BENLYSTA significantly reduced lupus disease activity mainly related to improvements in the immune system, muscles, joints, and skin. Significantly reduced risk of severe flares in two of the three studies, and reduced steroid dose by 25% or more during weeks 40 through 52 in patients receiving 7.5 milligrams or higher daily dose of steroid at the start of the studies.

ON-SCREEN TEXT:
LUPUS
In three clinical studies of adult patients with active lupus, BENLYSTA*:

Significantly reduced lupus disease activity mainly related to improvements in the immune system, muscles, joints, and skin.†
Significantly reduced risk of severe flares in two of the three studies.†
Reduced steroid dose by 25% or more (to a daily dose of 7.5 mg or less) during Weeks 40-52, in patients receiving 7.5 mg or higher daily doses of steroid at the start of the studies.†‡

* These studies were used in the FDA approval of BENLYSTA.
† Compared to other lupus medicines alone. ‡ A reduction of steroid dose was seen but was not statistically significant.
Results may vary.

NARRATOR:
In a two-year clinical study of adult patients with active lupus nephritis, BENLYSTA significantly reduced kidney disease activity with maintained kidney function, reduced protein in the urine, and reduced need for rescue medicines, and significantly reduce risk of kidney worsening.

ON-SCREEN TEXT:
LUPUS NEPHRITIS
In a 2-year clinical study of adult patients with active lupus nephritis, BENLYSTA:

Significantly reduced kidney disease activity with maintained kidney function, reduced protein in the urine, and reduced need for rescue medicines.*†
Significantly reduced risk of kidney worsening.*

* Compared to other lupus medicines alone.
† Rescue medicines such as steroids greater than 10 mg/day.
Results may vary.

ELIJAH:
If there's one thing I would've done differently, it would be to do more research on lupus symptoms. I think my fear kept me away because I felt like the more I knew about it, the less quality of life I would have.

ON-SCREEN TEXT:
Elijah’s Tip
Don’t be afraid to do research.

ELIJAH:
I also wish I had known more about what to look for in a doctor. I needed a doctor who would go beyond treating me based on bloodwork alone. When I found one, it made all the difference. With any sort of lupus treatment, I would say sometimes the quick fix isn't the best fix because it could just be covering something more serious. There are so many layers to lupus. It's a very sneaky disease. I think that's why they call it wolf's disease. So, be patient and try not to add stress by focusing on how fast the treatment is working, because the stress might make you feel worse. Some things may not work for you and other things will. Still, I stay in contact with my doctor and I let him know what I'm feeling and experiencing so we can make adjustments if needed.

ON-SCREEN TEXT:
Elijah’s Tip
Be patient and communicate with your doctor.

ELIJAH:
If I could speak directly to lupus, I'd honestly laugh and I'd say, I'm winning. Look at how much you're trying to hold me back and look at how much I keep taking these steps to beat you. Lupus, you should give up because now there's a whole army fighting against you. And if I could speak to another lupus warrior, I would say, "Don't be afraid to talk to your doctor about your treatment. If you have lupus or lupus nephritis, and it's still active with your current medications, ask your doctor if BENLYSTA is right for you.”

ON-SCREEN TEXT:
For financial assistance information, visit the Savings & Support tab of BENLYSTA.com.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

Important Safety Information

NARRATOR:
What is BENLYSTA?
BENLYSTA is a prescription medicine for adults with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis on other lupus medicines. BENLYSTA is not for people with severe active central nervous system lupus.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

What is BENLYSTA?
BENLYSTA is a prescription medicine for adults with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis on other lupus medicines. BENLYSTA is not for people with severe active central nervous system lupus.

NARRATOR:
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.

The most important information about BENLYSTA
Immunosuppressive agents, including BENLYSTA, can cause serious side effects. Some of these may cause death.

Infections: fever, chills, pain or burning with urination, urinating often, coughing up mucus, or warm, red, or painful skin or sores on your body. Infections could be serious, leading to hospitalization or death.
Allergic (hypersensitivity) reactions: itching, swelling of the face, lips, mouth, tongue, or throat, trouble breathing, anxiousness, low blood pressure, dizziness or fainting, headache, nausea, or skin rash. Serious allergic reactions can happen the day of, or in days after, receiving BENLYSTA and may cause death.
Mental health problems and suicide: thoughts of suicide or dying, attempt to commit suicide, trouble sleeping (insomnia), new or worse anxiety or depression, acting on dangerous impulses, other unusual changes in your behavior or mood, or thoughts of hurting yourself or others.

Before receiving BENLYSTA, discuss with your healthcare provider if you:

think you have an infection or have infections that keep coming back. Do not use BENLYSTA if you have an infection unless your healthcare provider tells you to.
have or have had mental health problems such as depression or thoughts of suicide.
have recently received or may need a vaccination. If you are receiving BENLYSTA, you should not receive live vaccines.
are taking any medicines, including prescription, over-the-counter, vitamins, and herbal supplements.
are allergic to other medicines.
are receiving other biologic medicines.
have or have had any type of cancer.
have any other medical conditions.
are pregnant or plan to become pregnant. It is unknown if BENLYSTA will harm your unborn baby. Talk to your healthcare provider about whether to prevent pregnancy while on BENLYSTA. If you choose to prevent pregnancy, you should use an effective method of birth control for at least 4 months after the final dose of BENLYSTA.
become pregnant while receiving BENLYSTA, talk to your healthcare provider about enrolling in the BENLYSTA Pregnancy Registry. You can enroll in this registry by calling 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/benlysta-belimumab/.
are breastfeeding or plan to breastfeed. It is unknown if BENLYSTA passes into your breast milk.

Possible side effects of BENLYSTA

Progressive multifocal leukoencephalopathy (PML). PML is a serious and life-threatening brain infection. PML can result in death or severe disability. Tell your healthcare provider right away if you notice any new or worsening medical problems: memory loss, trouble thinking, dizziness or loss of balance, difficulty talking or walking, or loss of vision.
Cancer. Medicines that affect the immune system, including BENLYSTA, may increase your risk of certain cancers.

The most common side effects of BENLYSTA are nausea, diarrhea, fever, stuffy or runny nose and sore throat, persistent cough, trouble sleeping, leg or arm pain, depression, headache, and pain, redness, itching, or swelling at the site of injection (when given subcutaneously). These are not all the possible side effects of BENLYSTA. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

ON-SCREEN TEXT:
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.

The most important information about BENLYSTA
Immunosuppressive agents, including BENLYSTA, can cause serious side effects. Some of these may cause death.

Infections: fever, chills, pain or burning with urination, urinating often, coughing up mucus, or warm, red, or painful skin or sores on your body. Infections could be serious, leading to hospitalization or death.
Allergic (hypersensitivity) reactions: itching, swelling of the face, lips, mouth, tongue, or throat, trouble breathing, anxiousness, low blood pressure, dizziness or fainting, headache, nausea, or skin rash. Serious allergic reactions can happen the day of, or in days after, receiving BENLYSTA and may cause death.
Mental health problems and suicide: thoughts of suicide or dying, attempt to commit suicide, trouble sleeping (insomnia), new or worse anxiety or depression, acting on dangerous impulses, other unusual changes in your behavior or mood, or thoughts of hurting yourself or others.

Before receiving BENLYSTA, discuss with your healthcare provider if you:

think you have an infection or have infections that keep coming back. Do not use BENLYSTA if you have an infection unless your healthcare provider tells you to.
have or have had mental health problems such as depression or thoughts of suicide.
have recently received or may need a vaccination. If you are receiving BENLYSTA, you should not receive live vaccines.
are taking any medicines, including prescription, over-the-counter, vitamins, and herbal supplements.
are allergic to other medicines.
are receiving other biologic medicines.
have or have had any type of cancer.
have any other medical conditions.
are pregnant or plan to become pregnant. It is unknown if BENLYSTA will harm your unborn baby. Talk to your healthcare provider about whether to prevent pregnancy while on BENLYSTA. If you choose to prevent pregnancy, you should use an effective method of birth control for at least 4 months after the final dose of BENLYSTA.
become pregnant while receiving BENLYSTA, talk to your healthcare provider about enrolling in the BENLYSTA Pregnancy Registry. You can enroll in this registry by calling 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/benlysta-belimumab/.
are breastfeeding or plan to breastfeed. It is unknown if BENLYSTA passes into your breast milk.

Possible side effects of BENLYSTA

Progressive multifocal leukoencephalopathy (PML). PML is a serious and life-threatening brain infection. PML can result in death or severe disability. Tell your healthcare provider right away if you notice any new or worsening medical problems: memory loss, trouble thinking, dizziness or loss of balance, difficulty talking or walking, or loss of vision.
Cancer. Medicines that affect the immune system, including BENLYSTA, may increase your risk of certain cancers.

The most common side effects of BENLYSTA are nausea, diarrhea, fever, stuffy or runny nose and sore throat, persistent cough, trouble sleeping, leg or arm pain, depression, headache, and pain, redness, itching, or swelling at the site of injection (when given subcutaneously). These are not all the possible side effects of BENLYSTA. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
For US audiences only.
Trademarks are owned by or licensed to the GSK group of companies.
©2023 GSK or licensor.
BELVID230017 November 2023
Produced in USA.

close

If I could speak directly to lupus, I would honestly laugh and say, ‘I’m winning.’”

Morgan

Enjoys fishing and her pets
Lupus
Started BENLYSTA in 2011

After trying several treatment combinations, Morgan didn’t feel her lupus symptoms were well-managed. But when she asked what more she could be doing to help manage her lupus, her doctor suggested adding BENLYSTA.

Managing Lupus
Starting BENLYSTA

Show Transcript

NARRATOR:
What is BENLYSTA?
BENLYSTA is a prescription medicine for adults with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis on other lupus medicines. It is not known if BENLYSTA is safe and effective in people with severe active central nervous system lupus.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

What is BENLYSTA?
BENLYSTA is a prescription medicine for adults with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis on other lupus medicines.
It is not known if BENLYSTA is safe and effective in people with severe active central nervous system lupus.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
Important Safety Information
Do not receive BENLYSTA if you are allergic to belimumab or to any of the ingredients in BENLYSTA. Please see complete Prescribing Information, including Medication Guide, at BENLYSTA.com.

NARRATOR:
Important Safety Information
Do not receive BENLYSTA if you are allergic to belimumab or to any of the ingredients in BENLYSTA.
Remember to watch the complete video to see additional safety information.

MORGAN:
Hey. I am Morgan. I am 32 years old, and I am from South Carolina. I'm married to a great guy named Tim. On my days off, I love to be outside, near the water, maybe at the beach, and I do enjoy fishing. This is my experience.

ON-SCREEN TEXT:
Real patient compensated by GSK.

MORGAN:
When I was 10 or 11, I knew it wasn't normal that I was experiencing joint pain, weakness, muscle fatigue, trouble opening certain, you know, a bottle of water or a can of soda. For me, it was very tough growing up like that because there are so many things that go into it, and not being able to enjoy some of the simple things in life.

MORGAN:
It took a long time to get my lupus diagnosis. There is no specific test that shows that you have lupus. When the doctor told me that I had SLE lupus, it was relief. It was knowing that this wasn't in my head. It wasn't imaginary.

MORGAN:
Looking back, I felt like it was kind of like a caged animal. It was really, really tough. Lupus isn't the main thing that defines me. I work a full-time job, I live a wonderful life with my husband, and truly just enjoy it. Having a good attitude and helping other people I think has made me the person I am today. I try to help people understand what it's like having lupus. I would tell them to, be an advocate for yourself, ask those hard questions, and really do your research. This is your life. This is your journey with lupus. Find a doctor that you can be comfortable with and that you can partner with; somebody that you can have those conversations and- and really feel like they are your best advocate also.

ON-SCREEN TEXT:
Lupus isn’t the main thing that defines me
Be an advocate for yourself
Find a doctor you are comfortable with

MORGAN:
When I started with my doctor, we tried a lot of combinations of medications to treat my lupus. My symptoms were not controlled, so my doctor suggested that we start BENLYSTA. At first, I was very scared trying a biologic medication. I didn't know what BENLYSTA was and what it meant. I didn't know what it would do for the rest of my life. I had to ask all those questions. My doctor gave me the information that we were looking for and was able to kind of help me understand.

ON-SCREEN TEXT:
This is Morgan’s experience. Yours may vary.

ON-SCREEN TEXT:
BENLYSTA is an add-on therapy.

ON-SCREEN TEXT:
A biologic therapy is a treatment derived from living tissues or cells.

MORGAN:
I decided to give BENLYSTA a try, and I started out on the IV formulation. The infusion center was a little intimidating. I did what I always do. I asked a lot of questions and definitely felt a little bit better about the situation.

ON-SCREEN TEXT:
IV formulation = intravenous formulation

MORGAN:
After a while, going and receiving my BENLYSTA was just routine. It was normal. Taking that afternoon off one time a month was tough. I work 40 to 50 hours a week, and not having that flexibility was tough. So, I spoke with my doctor and we decided that I should try the self-injection. My doctor showed me how to do the auto-injection, and I remember the first time that I did it, I was nervous and scared. But after each time, I definitely grew in confidence, and now I feel very comfortable doing them. I like the convenience of a self-injection. I can live my life my way, and I don't have to schedule my life around my infusions.

ON-SCREEN TEXT:
Morgan was trained by her doctor on how to use the autoinjector.

ON-SCREEN TEXT:
Self-injection works at home for Morgan’s life

MORGAN:
Without lupus, I really don't know the type of person I would be. I'm the type of person that rescues dogs and flea-infested cats, and old birds. And that's the type of person that lupus has made me. But if I could tell lupus off, I'd say, "Leave me alone. I'm going to push forward. Sorry, lupus. Not today."

NARRATOR:
Ready to say, "Sorry, Lupus"? Whether you have lupus or lupus nephritis, adding BENLYSTA may help. Financial assistance is available. Ask your doctor about BENLYSTA.

ON-SCREEN TEXT:
ASK YOUR DOCTOR ABOUT BENLYSTA

ON-SCREEN TEXT:
For financial assistance information, visit the Benefits & Savings tab of BENLYSTA.com.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
Important Safety Information

NARRATOR:
What is BENLYSTA?
BENLYSTA is a prescription medicine for adults with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis on other lupus medicines. It is not known if BENLYSTA is safe and effective in people with severe active central nervous system lupus.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

What is BENLYSTA?
BENLYSTA is a prescription medicine for adults with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis on other lupus medicines. It is not known if BENLYSTA is safe and effective in people with severe active central nervous system lupus.

NARRATOR:
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.

The most important information about BENLYSTA
Immunosuppressive agents, including BENLYSTA, can cause serious side effects. Some of these may cause death.

Infections: fever, chills, pain or burning with urination, urinating often, coughing up mucus, or warm, red, or painful skin or sores on your body. Infections could be serious, leading to hospitalization or death.
Allergic (hypersensitivity) reactions: itching, swelling of the face, lips, mouth, tongue, or throat, trouble breathing, anxiousness, low blood pressure, dizziness or fainting, headache, nausea, or skin rash. Serious allergic reactions can happen the day of, or in days after, receiving BENLYSTA and may cause death.
Mental health problems and suicide: thoughts of suicide or dying, attempt to commit suicide, trouble sleeping (insomnia), new or worse anxiety or depression, acting on dangerous impulses, other unusual changes in your behavior or mood, or thoughts of hurting yourself or others.

Before receiving BENLYSTA, discuss with your healthcare provider if you:

think you have an infection or have infections that keep coming back. Do not use BENLYSTA if you have an infection unless your healthcare provider tells you to.
have or have had mental health problems such as depression or thoughts of suicide.
have recently received or may need a vaccination. If you are receiving BENLYSTA, you should not receive live vaccines.
are taking any medicines, including prescription, over-the-counter, vitamins, and herbal supplements.
are allergic to other medicines.
are receiving other biologic medicines.
have or have had any type of cancer.
have any other medical conditions.
are pregnant or plan to become pregnant. It is unknown if BENLYSTA will harm your unborn baby. Talk to your healthcare provider about whether to prevent pregnancy while on BENLYSTA. If you choose to prevent pregnancy, you should use an effective method of birth control for at least 4 months after the final dose of BENLYSTA.
become pregnant while receiving BENLYSTA, talk to your healthcare provider about enrolling in the BENLYSTA Pregnancy Registry. You can enroll in this registry by calling 1-877-311-8972 or go to mothertobaby.org/ongoing-study/benlysta-belimumab/.
are breastfeeding or plan to breastfeed. It is unknown if BENLYSTA passes into your breast milk.

Possible side effects of BENLYSTA

Progressive multifocal leukoencephalopathy (PML). PML is a serious and life-threatening brain infection. PML can result in death or severe disability. Tell your healthcare provider right away if you notice any new or worsening medical problems: memory loss, trouble thinking, dizziness or loss of balance, difficulty talking or walking, or loss of vision.
Cancer. Medicines that affect the immune system, including BENLYSTA, may increase your risk of certain cancers.

The most common side effects of BENLYSTA are nausea, diarrhea, fever, stuffy or runny nose and sore throat, persistent cough, trouble sleeping, leg or arm pain, depression, headache, and pain, redness, itching, or swelling at the site of injection (when given subcutaneously). These are not all the possible side effects of BENLYSTA. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

ON-SCREEN TEXT:
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.

The most important information about BENLYSTA
Immunosuppressive agents, including BENLYSTA, can cause serious side effects. Some of these may cause death.

Infections: fever, chills, pain or burning with urination, urinating often, coughing up mucus, or warm, red, or painful skin or sores on your body. Infections could be serious, leading to hospitalization or death.
Allergic (hypersensitivity) reactions: itching, swelling of the face, lips, mouth, tongue, or throat, trouble breathing, anxiousness, low blood pressure, dizziness or fainting, headache, nausea, or skin rash. Serious allergic reactions can happen the day of, or in days after, receiving BENLYSTA and may cause death.
Mental health problems and suicide: thoughts of suicide or dying, attempt to commit suicide, trouble sleeping (insomnia), new or worse anxiety or depression, acting on dangerous impulses, other unusual changes in your behavior or mood, or thoughts of hurting yourself or others.

Before receiving BENLYSTA, discuss with your healthcare provider if you:

think you have an infection or have infections that keep coming back. Do not use BENLYSTA if you have an infection unless your healthcare provider tells you to.
have or have had mental health problems such as depression or thoughts of suicide.
have recently received or may need a vaccination. If you are receiving BENLYSTA, you should not receive live vaccines.
are taking any medicines, including prescription, over-the-counter, vitamins, and herbal supplements.
are allergic to other medicines.
are receiving other biologic medicines.
have or have had any type of cancer.
have any other medical conditions.
are pregnant or plan to become pregnant. It is unknown if BENLYSTAwill harm your unborn baby. Talk to your healthcare provider about whether to prevent pregnancy while on BENLYSTA. If you choose to prevent pregnancy, you should use an effective method of birth control for at least 4 months after the final dose of BENLYSTA.
become pregnant while receiving BENLYSTA, talk to your healthcare provider about enrolling in the BENLYSTA Pregnancy Registry. You can enroll in this registry by calling 1-877-311-8972 or go to mothertobaby.org/ongoing-study/benlysta-belimumab/.
are breastfeeding or plan to breastfeed. It is unknown if BENLYSTA passes into your breast milk.

Possible side effects of BENLYSTA

Progressive multifocal leukoencephalopathy (PML). PML is a serious and life-threatening brain infection. PML can result in death or severe disability. Tell your healthcare provider right away if you notice any new or worsening medical problems: memory loss, trouble thinking, dizziness or loss of balance, difficulty talking or walking, or loss of vision.
Cancer. Medicines that affect the immune system, including BENLYSTA, may increase your risk of certain cancers.

The most common side effects of BENLYSTA are nausea, diarrhea, fever, stuffy or runny nose and sore throat, persistent cough, trouble sleeping, leg or arm pain, depression, headache, and pain, redness, itching, or swelling at the site of injection (when given subcutaneously). These are not all the possible side effects of BENLYSTA. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
For US audiences only.
Trademarks are owned by or licensed to the GSK group of companies.
©2023 GSK or licensor.
BELVID230019 November 2023
Produced in USA.

close

If I could tell lupus off, I’d say, ‘Leave me alone, I’m going to push forward. Sorry lupus, not today.’”

Show Transcript

NARRATOR:
What is BENLYSTA?
BENLYSTA is a prescription medicine for adults with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis on other lupus medicines. BENLYSTA is not for people with severe active central nervous system lupus.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

What is BENLYSTA?
BENLYSTA is a prescription medicine for adults with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis on other lupus medicines. BENLYSTA is not for people with severe active central nervous system lupus.

NARRATOR:
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.
Please click the Important Safety Information tab to the left to watch or hear the Important Safety Information about BENLYSTA.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

Important Safety Information
Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.
Please see complete Prescribing Information, including Medication Guide, at BENLYSTA.com.

ON-SCREEN TEXT:

BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
Switching from IV to SC

MORGAN:
My name is Morgan. I'm 32 years old, and I live in South Carolina, and this is my experience. When I started with my doctor, we tried a lot of combinations of medications to treat and manage my lupus. My symptoms were not controlled, so that's when my doctor suggested that we try adding BENLYSTA. I started off with the IV formulation but I was working 40 to 50 hours per week. It was becoming hard to get that afternoon off each month, and so having that flexibility was what I really was going for.

ON-SCREEN TEXT:
Real patient compensated by GSK.

MORGAN:
I used to have to plan my scheduled infusions, so I talked with my doctor and we decided we would try the self-injection.

ON-SCREEN TEXT:
Morgan’s doctor’s office trained her on how to self-inject.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
Copay Support

MORGAN:
My copay benefits continued when I switched to the BENLYSTA autoinjector.

ON-SCREEN TEXT:
Real patient compensated by GSK.

NARRATOR:
To participate in BENLYSTA Copay Program, work with your doctor to enroll in BENLYSTA Gateway or go to BENLYSTACopayProgram.com to register and see if you're eligible. Renewal is once a year.

ON-SCREEN TEXT:
The BENLYSTA Copay Program may help eligible commercially insured patients with their out-of-pocket costs for BENLYSTA.
Eligibility restrictions and program maximums apply. Visit www.GSKCopayPrograms.com for complete Program Terms and Conditions.

MORGAN:
My doctor's office let the BENLYSTA Gateway know about the change to my prescription and got me connected to the specialty pharmacy. This was my experience with BENLYSTA Gateway, so be sure to reach out to them to let them know about your prescription change. BENLYSTA Gateway also told my doctor's office about my new insurance since I had different coverage previously. Gateway can help you understand this as well.

ON-SCREEN TEXT:
SPECIALTY PHARMACY
Pharmacies that dispense particular medications for certain conditions.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
Morgan’s tips for working with your Specialty Pharmacy

MORGAN:
The specialty pharmacy will call you to help arrange the delivery of your autoinjector. Watch for a call from a number you may not recognize.

ON-SCREEN TEXT:
Real patient compensated by GSK.

MORGAN:
Make sure to return their calls because they cannot ship your BENLYSTA without speaking to you first. You might want to add that number to your phone because they'll call you each month to set up your shipment and your copay.

ON-SCREEN TEXT:
MORGAN’S TIPS
1. Answer your phone when the specialty pharmacy calls.
2. Be sure to return their calls.
3. Add them as a contact in your phone.

MORGAN:
For renewals, they actually call me about 30 days ahead.

MORGAN:
The specialty pharmacy will send your BENLYSTA autoinjector to where it's convenient for you.

ON-SCREEN TEXT:
MORGAN’S TIPS
Get your BENLYSTA shipped to your home or office, wherever it is convenient for you.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
What to expect in your package

MORGAN:
So, when you open it up, the information will be in there about what's in the box, and then information about BENLYSTA and the drug facts. If you're getting this shipment for the first time, you'll also get a kit to help with your first injection.

ON-SCREEN TEXT:
Real patient compensated by GSK. Injection training kit is subject to availability.

ON-SCREEN TEXT:
After being trained by a healthcare provider, you can self-inject BENLYSTA from the comfort of your own home with a once-weekly subcutaneous injection.

MORGAN:
It was nice having the BENLYSTA Cares nurses there available to walk me through the process over the phone, if I needed them. It's layered with ice packs so it's shipped refrigerated. I get a 4-week supply at one time, one large, rectangular box. Lift up the lid and you'll see each subcutaneous injection is within its own little plastic pouch. I just pop the box in the fridge, then once a week I pull one out, wait 30 minutes to bring it to room temperature and I'm ready to do my injection. I really look forward to getting my BENLYSTA each month. It really is that easy to unpack and put away.

ON-SCREEN TEXT:
BENLYSTA CARES logo
1-877-4-BENLYSTA (1-877-423-6597) Monday to Friday 8 am to 8 pm
Nurses from BENLYSTA Cares do not give medical advice, and will direct you to your healthcare provider for any disease-, treatment-, or referral-related questions.

ON-SCREEN TEXT:
If you have lupus nephritis, one dose may be 2 injections.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
Important Safety Information

NARRATOR:
What is BENLYSTA?
BENLYSTA is a prescription medicine for adults with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis on other lupus medicines. BENLYSTA is not for people with severe active central nervous system lupus.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL

What is BENLYSTA?
BENLYSTA is a prescription medicine for adults with active systemic lupus erythematosus (SLE or lupus) or active lupus nephritis on other lupus medicines. BENLYSTA is not for people with severe active central nervous system lupus.

NARRATOR:
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.

The most important information about BENLYSTA

Immunosuppressive agents, including BENLYSTA, can cause serious side effects. Some of these may cause death.
Infections: fever, chills, pain or burning with urination, urinating often, coughing up mucus, or warm, red, or painful skin or sores on your body. Infections could be serious, leading to hospitalization or death.
Allergic (hypersensitivity) reactions: itching, swelling of the face, lips, mouth, tongue, or throat, trouble breathing, anxiousness, low blood pressure, dizziness or fainting, headache, nausea, or skin rash. Serious allergic reactions can happen the day of, or in days after, receiving BENLYSTA and may cause death.
Mental health problems and suicide: thoughts of suicide or dying, attempt to commit suicide, trouble sleeping (insomnia), new or worse anxiety or depression, acting on dangerous impulses, other unusual changes in your behavior or mood, or thoughts of hurting yourself or others.

Before receiving BENLYSTA, discuss with your healthcare provider if you:

think you have an infection or have infections that keep coming back. Do not use BENLYSTA if you have an infection unless your healthcare provider tells you to.
have or have had mental health problems such as depression or thoughts of suicide.
have recently received or may need a vaccination. If you are receiving BENLYSTA, you should not receive live vaccines.
are taking any medicines, including prescription, over-the-counter, vitamins, and herbal supplements.
are allergic to other medicines.
are receiving other biologic medicines.
have or have had any type of cancer.
have any other medical conditions.
are pregnant or plan to become pregnant. It is unknown if BENLYSTA will harm your unborn baby. Talk to your healthcare provider about whether to prevent pregnancy while on BENLYSTA. If you choose to prevent pregnancy, you should use an effective method of birth control for at least 4 months after the final dose of BENLYSTA.
become pregnant while receiving BENLYSTA, talk to your healthcare provider about enrolling in the BENLYSTA Pregnancy Registry. You can enroll in this registry by calling 1-877-311-8972 or go to mothertobaby.org/ongoing-study/benlysta-belimumab/.
are breastfeeding or plan to breastfeed. It is unknown if BENLYSTA passes into your breast milk.

Possible side effects of BENLYSTA

Progressive multifocal leukoencephalopathy (PML). PML is a serious and life-threatening brain infection. PML can result in death or severe disability. Tell your healthcare provider right away if you notice any new or worsening medical problems: memory loss, trouble thinking, dizziness or loss of balance, difficulty talking or walking, or loss of vision.
Cancer. Medicines that affect the immune system, including BENLYSTA, may increase your risk of certain cancers.

The most common side effects of BENLYSTA are nausea, diarrhea, fever, stuffy or runny nose and sore throat, persistent cough, trouble sleeping, leg or arm pain, depression, headache, and pain, redness, itching, or swelling at the site of injection (when given subcutaneously). These are not all the possible side effects of BENLYSTA. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

ON-SCREEN TEXT:
Important Safety Information
Do not use BENLYSTA if you are allergic to belimumab or any ingredients in BENLYSTA.
The most important information about BENLYSTA
Immunosuppressive agents, including BENLYSTA, can cause serious side effects. Some of these may cause death.

Infections: fever, chills, pain or burning with urination, urinating often, coughing up mucus, or warm, red, or painful skin or sores on your body. Infections could be serious, leading to hospitalization or death.
Allergic (hypersensitivity) reactions: itching, swelling of the face, lips, mouth, tongue, or throat, trouble breathing, anxiousness, low blood pressure, dizziness or fainting, headache, nausea, or skin rash. Serious allergic reactions can happen the day of, or in days after, receiving BENLYSTA and may cause death.
Mental health problems and suicide: thoughts of suicide or dying, attempt to commit suicide, trouble sleeping (insomnia), new or worse anxiety or depression, acting on dangerous impulses, other unusual changes in your behavior or mood, or thoughts of hurting yourself or others.
Before receiving BENLYSTA, discuss with your healthcare provider if you:
think you have an infection or have infections that keep coming back. Do not use BENLYSTA if you have an infection unless your healthcare provider tells you to.
have or have had mental health problems such as depression or thoughts of suicide.
have recently received or may need a vaccination. If you are receiving BENLYSTA, you should not receive live vaccines.
are taking any medicines, including prescription, over-the-counter, vitamins, and herbal supplements.
are allergic to other medicines.
are receiving other biologic medicines.
have or have had any type of cancer.
have any other medical conditions.
are pregnant or plan to become pregnant. It is unknown if BENLYSTAwill harm your unborn baby. Talk to your healthcare provider about whether to prevent pregnancy while on BENLYSTA. If you choose to prevent pregnancy, you should use an effective method of birth control for at least 4 months after the final dose of BENLYSTA.
become pregnant while receiving BENLYSTA, talk to your healthcare provider about enrolling in the BENLYSTA Pregnancy Registry. You can enroll in this registry by calling 1-877-311-8972 or go to mothertobaby.org/ongoing-study/benlysta-belimumab/.
are breastfeeding or plan to breastfeed. It is unknown if BENLYSTA passes into your breast milk.

Possible side effects of BENLYSTA

Progressive multifocal leukoencephalopathy (PML). PML is a serious and life-threatening brain infection. PML can result in death or severe disability. Tell your healthcare provider right away if you notice any new or worsening medical problems: memory loss, trouble thinking, dizziness or loss of balance, difficulty talking or walking, or loss of vision.
Cancer. Medicines that affect the immune system, including BENLYSTA, may increase your risk of certain cancers.

The most common side effects of BENLYSTA are nausea, diarrhea, fever, stuffy or runny nose and sore throat, persistent cough, trouble sleeping, leg or arm pain, depression, headache, and pain, redness, itching, or swelling at the site of injection (when given subcutaneously). These are not all the possible side effects of BENLYSTA. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

ON-SCREEN TEXT:
BENLYSTA (belimumab)
Intravenous Use 120 mg/vial
Subcutaneous Use 200 mg/mL
For US audiences only.
Trademarks are owned by or licensed to the GSK group of companies.
©2023 GSK or licensor.
BELVID230030 November 2023
Produced in USA.

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