Banner: Taking BENLYSTA



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In a clinical study in Black patients with lupus, a reduction in disease activity was seen but was not statistically significant. Ask your doctor about BENLYSTA.

Whether you have lupus or active lupus nephritis, with BENLYSTA you have a choice.


There are two ways to take BENLYSTA:

  • Self-injection at home: for adults with lupus and/or lupus nephritis
  • Intravenous infusion administered by a healthcare provider: for adults with lupus and/or lupus nephritis and for children with lupus (aged 5-17 years)

Ask your doctor which BENLYSTA option is right for you.


Subcutaneous (SC) Use (BENLYSTA Injection) 

At-home administration
After being trained by a healthcare provider, you can self-inject BENLYSTA from the comfort of your own home with a once-weekly subcutaneous injection.



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Intravenous (IV) Use (BENLYSTA Infusion)


In-office administration

When beginning treatment with BENLYSTA IV, it is recommended that you receive infusions from a healthcare provider every 2 weeks for the first 3 doses, and every 4 weeks thereafter. Infusions are usually given at a doctor’s office or an infusion center.



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Your overview of BENLYSTA Dosing Options


Dosing for SC in adult patients: At-home administration


* The 400-mg dose requires administration of 2 autoinjectors (2 x 200 mg). When the 400-mg dose is administered at the same site, it is recommended that the 2 individual 200-mg injections be administered at least 5 cm (approximately 2 inches) apart.



Dosing for IV: In-office administration

Did you know? In a small survey with adult patients with lupus who switched from receiving BENLYSTA via IV infusion to the BENLYSTA autoinjector, 3 out of 4 preferred the autoinjector. Your experience may be different.

Frequently Asked Questions

  • I’m currently receiving monthly BENLYSTA IV infusions. Can I switch to the autoinjector?

    You may be a candidate for BENLYSTA at-home administration with the autoinjector. Talk to your doctor to see if switching to the BENLYSTA autoinjector is right for you.

    If you and your doctor decide that you should switch, BENLYSTA Gateway is there to help you through the process.

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  • What is the BENLYSTA Co-pay Program?

    The BENLYSTA Co-Pay Program helps eligible approved patients with their out-of-pocket costs for BENLYSTA up to $15,000 for 12 months.

    If approved, patients could pay as little as $0 for BENLYSTA.

    Patients in government-funded programs (eg, Medicare, Medicaid, VA, or TRICARE) are not eligible for the BENLYSTA Co-pay Program. Medicare-eligible patients who are enrolled in certain retiree drug benefit plans are also ineligible for the co-pay program. (Most patients become eligible for Medicare when they reach age 65.)

    Patients must submit an Enrollment Form or complete eligibility check online at so their eligibility can be determined. Click here for full Program Terms and Conditions.


    Call  1-877-4-BENLYSTA (1-877-423-6597) from 8 AM to 8 PM Eastern Time, Monday through Friday.



    Complete a BENLYSTA Co-Pay Program eligibility check on

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  • Can I take BENLYSTA if I am pregnant or plan to become pregnant?

    Before you receive BENLYSTA, tell your healthcare provider if you are pregnant or plan to become pregnant. It is not known if BENLYSTA will harm your unborn baby. You should talk to your healthcare provider about whether to prevent pregnancy while on BENLYSTA. If you choose to prevent pregnancy, you should use an effective method of birth control while receiving BENLYSTA and for at least 4 months after the final dose of BENLYSTA. Tell your healthcare provider right away if you become pregnant during your treatment with BENLYSTA or if you think you may be pregnant.

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Want to learn more about resources for BENLYSTA?

Whether you are just getting started with BENLYSTA, or have been taking BENLYSTA for a while, BENLYSTA Cares offers support and ongoing resources throughout the course of your treatment.



Discover the BENLYSTA experience

Hear from real patients about their experiences living with lupus and with BENLYSTA treatment.