BENLYSTA Infusion for Intravenous Use 

For some, the idea of self-injection can be overwhelming. There is another way to receive BENLYSTA. Learn about BENLYSTA for Intravenous Use (IV), infusions given by a healthcare professional.

What You Need to Know


When you are administered BENLYSTA by your healthcare provider, you will be monitored before, during, and immediately after the infusion.

Diagram: BENLYSTA Dosing Guide

Where it happens

  • For BENLYSTA IV, your healthcare provider will discuss the most suitable place for you to receive your infusion.
  • You may receive your infusion at your doctor's office, a hospital, or an infusion center.

How long it takes

  • The infusion of BENLYSTA is given over approximately one hour.
  • Preparation time before and observation time after the infusion may vary.

How often it happens

Here is the recommended dosing schedule for BENLYSTA IV:

  • For the first three IV infusions, BENLYSTA is given every 2 weeks.
  • After that, BENLYSTA is given once every 4 weeks. See the accompanying diagram as an example.
  • It's important to continue to receive BENLYSTA as prescribed, even if you're feeling better. And if you’re not feeling better right away, talk to your doctor about how BENLYSTA takes time to work in your body.
  • Talk to your doctor if you experience any side effects.

Icon: BENLYSTA for Intravenous Use

Before and After Your BENLYSTA Infusion


Before your infusion
Your healthcare provider will prepare you for your infusion of BENLYSTA. They will do this by asking questions about how you’re feeling and your medical history, in addition to taking measurements, such as temperature, pulse rate, and blood pressure. Your healthcare provider may give you medication such as an antihistamine before you receive BENLYSTA to help reduce your chance of having an allergic reaction.


After your infusion
It is common to feel some discomfort where the IV line was inserted. This discomfort should go away within a few hours. You may also feel a little drowsy if you took an antihistamine and may want to go home and rest. For this reason, you may want to consider having someone drive you home from your infusion. Depending on how you feel, you may be able to return to your usual activities. Contact your healthcare provider if you don't feel well or have soreness or tenderness at the infusion site that does not go away.



The infusion experience

Learn from patients about starting BENLYSTA IV    


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Important tips to remember



Preparing for your infusion

  • Your healthcare provider will take your vitals and weight to calculate the dosage.
  • Talk to your healthcare provider if you have questions about the infusion process.

After your infusion

  • You may be drowsy. Ensure somebody is there to drive you home.
  • You may have some mild discomfort where the IV line was inserted.
  • If you don’t feel well or have soreness at the infusion site that doesn’t disappear after a few hours, contact your healthcare provider.

Allergic (hypersensitivity) and infusion reactions

  • Serious reactions can happen on the day of —or in the days after— receiving BENLYSTA and may cause death.
  • Tell your healthcare provider right away if you have any of the following symptoms of a reaction: itching; swelling of the face, lips, mouth, tongue, or throat; trouble breathing; anxiousness; low blood pressure; dizziness or fainting; headache; nausea; or skin rash, redness, or swelling.
  • Tell your healthcare provider or get emergency medical help right away if you have any of these symptoms.
Questions or Concerns

It’s normal to have questions or concerns regarding a new treatment. Be sure you ask your healthcare provider what to do if:

  • You miss your infusion appointment.
  • You are unsure how often you should receive BENLYSTA.
  • You think you feel better and want to discontinue your treatment, as it is important to continue to receive BENLYSTA as prescribed. 

For more information on BENLYSTA IV, you can contact BENLYSTA Cares.


Call BENLYSTA Cares: 1-877-4-BENLYSTA (1-877-423-6597), 8 AM to 8 PM Eastern Time, Monday through Friday. 


Experience BENLYSTA


Discover stories from those living with lupus and using BENLYSTA. Listen to people discuss starting BENLYSTA, working with their healthcare team, building support systems, and sharing their tips for those with lupus.


Watch their stories


Frequently Asked Questions

  • Talk to your doctor. You should not make any changes in your medication regimen without first consulting with your doctor.

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  • BENLYSTA is not a chemotherapy drug.
    It is also not a steroid. BENLYSTA is a biology therapy that contains belimumab, which is in a group of medicines called monoclonal antibodies. Lupus is a disease of the immune system (the body system that fights infection). When given together with other medicines for lupus, BENLYSTA may help reduce the abnormal immune system activity that contributes to disease activity in lupus.

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  • You may be eligible for the Program if:


    • You have a commercial medical or prescription insurance plan; or you are uninsured
    • You are under the age of 65
    • You are a resident of the US (including the District of Columbia, Puerto Rico and the US Virgin Islands)


    You are not eligible for the Program if:


    • You have a state- or federal government-funded medical or prescription insurance plan such as Medicare, Medicaid, VA, or Tricare
    • You are Medicare-eligible (those who are aged 65 or older are deemed Medicare-eligible)
    • You are enrolled in a commercial health plan that does not permit the use of co-pay assistance programs

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Want to learn more about resources for BENLYSTA?

If you are just getting started with BENLYSTA infusion, or have been taking BENLYSTA for a while, BENLYSTA Cares offers support and ongoing resources throughout the course of your treatment.



Looking for BENLYSTA coverage assistance?

With BENLYSTA infusion treatment, you will also have access to understanding your health insurance coverage with BENLYSTA Gateway & Co-pay Savings Program.